Wouldn’t it be great to prevent the development of hydrocephalus? New research is getting us closer. In this webinar, Dr. Yun Yung from the Scripps Research Institute discusses his exciting new work focused on understanding and preventing post-hemorrhagic hydrocephalus. Learn about why brain bleeds may lead to hydrocephalus and the drugs being tested to prevent it.
To view the full recording, click here.
This webinar is ideal for anyone who wants to meet our former HA-sponsored Mentored Young Investigators and learn more about the latest in hydrocephalus research.
Yun Yung, PhD
The Scripps Research Institute
Yun Yung, PhD, was a graduate student at the Scripps Research Institute at the time of his Mentored Young Investigator (MYI) Award. In 2010, Yung completed his dissertation and moved from a Postdoctoral Fellow position to a Research Associate. Dr. Yung received an AB in neuroscience from the University of California, Berkeley and a PhD in neuroscience from the University of California, San Diego.
Dr. Yung’s research focus is to determine the role of the small lipid, lysophosphatidic acid or LPA, that has been identified as a cause of fetal hydrocephalus (FH) in mice. Dr. Yung’s MYI study explored whether there is a critical period during brain development in which intracranial bleeding is likely to lead to hydrocephalus. In addition, the study tested whether pharmacological blockade of LPA receptors in the brain can ameliorate FH. The researchers were able to show that FH occurred mainly through LPA1 signaling pathway. The researchers propose that the LPA1 signaling pathway is a molecular mechanism that may account for the observation linking prenatal bleeding and FH. They hypothesize that high concentration of LPA leads to the activation of LPA receptors expressed by neural progenitor cells, which in turn activate other intracellular signaling to produce disorganization and thinning of the cortical layers and, ultimately, FH.
We are pleased to offer educational webinars to help you stay informed and current on the latest news surrounding hydrocephalus. These interactive, free webinars are designed to educate our community on a variety of topics which include normal pressure hydrocephalus (NPH), research, shunt technology and more.
Our webinar series features presentations from medical professionals, researchers and others with a direct connection to hydrocephalus. Each webinar is moderated by HA’s Support and Education Staff and are archived and accessible following the event.
Please contact the Hydrocephalus Association by telephone (888) 598-3789 or via e-mail at Jennifer@hydroassoc.org.