Research UPDATE: A Clue to Better Understand and Treat Hydrocephalus

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Tamara_SimonShared from our friends at Seattle Children’s Hospital

Dr. Tamara Simon, MD, MSPH, and her research team from Seattle Children’s Hospital have discovered a clue that could help doctors better understand and treat hydrocephalus. Dr. Simon and her team used genetic sequencing to conduct the first-ever inventory of the complex assortment of bacteria and fungi found in the cerebrospinal fluid of eight children with shunt infections. They identified a surprisingly diverse variety of pathogens, many never before associated with shunt infections. This suggests that many different pathogens may conspire to drive the infections, indicating there might be something we can do to better treat and also prevent these difficult infections altogether.

See the Seattle Children’s blog post about the study here: Discovery could help prevent shunt infections, improve treatment for children with hydrocephalus.

Read the study abstract from PLOS ONE here: Evaluation of Microbial Bacterial and Fungal Diversity in Cerebrospinal Fluid Shunt Infection.


Dr. Tamara Simon, MD, MSPH, is an Assistant Professor of Pediatrics and a Pediatric Hospitalist at Children’s Hospital of Seattle. She is also the principal investigator for the shunt infection section of the Hydrocephalus Clinical Research Network’s (HCRN) Registry. She received a BA with honors in molecular biology from Colgate University, a MD with honors from the University of North Carolina at Chapel Hill School of Medicine and a Master’s of Science in Public Health (MSPH) from the University of Colorado at Denver.

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