2016 Innovator Award Recipient
TITLE: Director of Developmental Anomaly Neurosurgery
INSTITUTION: Yale School of Medicine
GOAL: Understanding the Role of the Choroid Plexus Epithelium (CPE) in Posthemorrhagic Hydrocephalus (PHH)
Dr. Kristopher Kahle is the Director of Developmental Anomaly Neurosurgery at the Yale School of Medicine. The research of Dr. Kahle is focused on the molecular mechanisms of damage to the choroid plexus. The choroid plexus is responsible for cerebrospinal fluid (CSF) production in the ventricles. In his study, Innate immunity and CSF production in posthemorrhagic hydrocephalus, Dr. Kahle will evaluate how intraventricular hemorrhage impacts choroid plexus CSF production. He is testing a new theory for why posthemorrhagic hydrocephalus develops after a brain bleed which could lead to new therapeutic targets.