Jerold Chun, MD, PhD, a professor at Scripps Research and its Dorris Neuroscience Center, has discovered a significant factor in the development of congenital hydrocephalus. Chun describes the discovery as a proof of concept that could lead to medical treatments for hydrocephalus. His finding involves the discovery of abnormally high levels of a lipid called LPA in the brains of mice that develop hydrocephalus. They have shown that prohibiting the buildup of excessive LPA has a preventative effect on the development of hydrocephalus. Dr. Chun’s findings were published today in the September 7, 2011, issue of the journal Science Translational Medicine.
We are honored to have Dr. Chun as the Review Chair for HA’s current round of research grants focused on cerebrospinal fluid dynamics. He is also the mentor to postdoctoral fellow Yun Yung, PhD, who was a grantee from our inaugural Mentored Young Investigators award in 2009 and contributed to these findings around LPA and congenital hydrocephalus. We are very excited about the potential for their findings and we congratulate Dr. Chun on the recent publication of his results. You can read more about his findings here.