Gravitational Valves Reduce the Incidence of overdrainage in Shunted iNPH Patients
The Hydrocephalus Association is pleased to share some exciting research on the usage of gravitational shunt valves in idiopathic normal pressure hydrocephalus (iNPH). The study, “Safety and efficacy of gravitational shunt valves in patients with idiopathic normal pressure hydrocephalus: a pragmatic, randomized, open label, multicentre trial (SVASONA)” published in the Journal of Neurology, Neurosurgery and Psychiatry in March 2013, features the Aesculap-Miethke proGAV Gravitational Shunt System. The study investigates whether gravitational shunt valves reduce the risk of overdrainage complications compared with programmable systems without gravitational valves for patients with iNPH. 145 patients were enrolled in the study from seven Hospital Centers in Europe. Results from the study showed that gravitational valves significantly reduced the incidence of overdrainage in shunted iNPH patients by a ratio of 1/3. In addition to the decrease in overdrainage, the study suggested improvements in mental domains and quality of life in patients with gravitational valves.
Lemcke J, et al. Safety and efficacy of gravitational shunt valves in patients with idiopathic normal pressure hydrocephalus: a pragmatic, randomized, open label, multicentre trial (SVASONA). J Neurol Neurosurg Psychiatry. 2013 Aug; 84(8):850-7